A Scientist in Wonderland

Edzard Ernst is one of those rare people who dare to question their own beliefs, look at the evidence without bias, and change their minds. He went from practicing alternative medicine to questioning it, to researching it, to becoming its most prolific critic. I have long admired his work, and I finally met him in

Another Misguided Cancer Testimonial

Mike Shedlock wrote a post about how he beat prostate cancer. In doing so, he provides a typical example of how difficult the medical literature can be for a layperson to read, and where they can get things wrong. The Dunning-Kruger effect, leading to false beliefs about nearly everything since the dawn of humanity. An

Smoking Cessation and the Affordable Care Act

Smoking is the leading preventable cause of death. Each year it kills more than 5 million people around the world, 480,000 in the US alone. And for every person who dies, about 30 more have serious illnesses caused by smoking. On average, smokers die 10 years earlier than nonsmokers. Anyone who is concerned about preventive medicine must consider

Is the Ebola Crisis a Reason to Skip RCTs?

In a recent “Perspective” article in The New England Journal of Medicine, three physicians (Drs. Cox, Borio, and Temple) make a strong case for not letting the rush to save Ebola patients tempt us to deviate from good science and skip the randomized controlled trial (RCT). Their arguments cut to the essence of the scientific approach to medicine,

Food Faiths and Diet Religions

  The parade of diet fads is unending; they will continue to proliferate as long as humans have to eat. They have created a hellish world in which every food component is a potential demon: fat, gluten, carbs, sugar, wheat, salt, etc. Diet gurus, both professional and amateur, are always ready to tell us what

Smokey the Bear Medicine and Prevention

When I was an intern, we used to joke that we were practicing “Smokey the Bear” medicine: stamping out forest fires. Patients would wait until a spark of disease had developed into a dangerous flame, and then they’d expect us to deal with it. We were mostly doing disaster control, and we wished we could

Colloidal Silver, Smurfs, and Ebola

Colloidal silver is back! It competed in the ring of science and was thoroughly clobbered. If it had any dignity, it would have stayed down for the count and admitted defeat; but like some bizarre whack-a-mole or zombie it keeps stumbling back to its feet, wanting to fight again. This myth that refuses to die

Evidence: “It Worked for My Aunt Tillie” Is Not Enough

Evidence means different things to different people. Even quacks and their victims claim to have evidence that their treatments work. Sometimes that evidence consists only of testimonials from satisfied customers or from personal experience. “I tried X and I got better.” “I know Y works because it cured my Aunt Tillie’s arthritis.” I had a

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