The Believing Brain

A common question of skeptics and science-based thinkers is “How could anyone believe that?” People do believe some really weird things and even some obviously false things. The more basic question is how we form all our beliefs, whether false or true. Michael Shermer’s book Why People Believe Weird Things has become a classic. Now

How to Build a Bridge

People tend to limit their reading to sources that agree with their beliefs. We find ourselves mostly preaching to the choir; our message usually doesn’t reach those who most need to hear it. I recently received an inquiry from a science-based medical doctor asking how to approach others in building a bridge to clarify so

Pragmatic Studies and Cinderella Medicine

Explanatory studies are done under controlled conditions to determine whether a treatment has any efficacy compared to a placebo. Pragmatic studies are designed to assess how the intervention performs in everyday real world practice. Pragmatic studies measure practical success but don’t determine actual efficacy: that requires a proper randomized controlled trial (RCT) with an appropriate

Cognitive Traps

In my recent review of Peter Palmieri’s book Suffer the Children I said I would later try to cover some of the many other important issues he brings up. One of the themes in the book is the process of critical thinking and the various cognitive traps doctors fall into. I will address some of

Hash Oil for Gliomas? What Would You Do?

A friend asked me to look at the evidence for hash oil as a treatment for glioma. His teenage daughter was recently diagnosed with brain cancer: a grade 3 anaplastic ependymoma. It recurred very rapidly after surgery and radiotherapy and the latest tissue diagnosis shows an aggressive grade IV glioma. Her prognosis is not good.

Two Views of the War on Cancer

Pink Ribbon Blues: How Breast Cancer Culture Undermines Women’s Health. By Gayle Sulik. Oxford University Press, New York, 2010. ISBN: 0199740453. 424 pp. Hardcover, $29.95.  The Emperor of All Maladies: A Biography of Cancer. By Siddhartha Mukherjee. Scribner, New York, 2010. ISBN: 978-1-4391-0795-9. 571 pp. Hardcover, $30. The pink ribbon is a widely recognized symbol

Suffer the Children

Some of our readers have complained that we pick on alternative medicine while ignoring the problems in conventional medicine. That criticism is unjustified: we oppose non-science-based medicine wherever we find it. We find it regularly in alternative medicine; we find it less frequently in conventional medicine, but when we do, we speak out.   A new

The Role of Experience in Science-Based Medicine

Before we had EBM (evidence-based medicine) we had another kind of EBM: experience-based medicine. Mark Crislip has said that the three most dangerous words in medicine are “In my experience.” I agree wholeheartedly. On the other hand, it would be a mistake to discount experience entirely. Dynamite is dangerous too, but when handled with proper

Frequencies and Their Kindred Delusions

The word “frequency” ranks right up there with “quantum” and “energy” as a pseudoscientific buzzword. It is increasingly prevalent in product advertisements and in CAM claims about human biofields and energy medicine. It doesn’t mean what they think it means. I have written about Power Balance products, the wristbands and cards that allegedly improve sports

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