New Drug Is Effective for Post-Partum Depression, But There Are Drawbacks

A new drug promises to cure postpartum depression, but it is restricted and patients must be hospitalized for a 60-hour IV infusion. There’s a new cure for postpartum depression; but don’t celebrate just yet. It’s far from a panacea, and it’s not for everyone. The devil is in the details. Post-partum depression (PPD) affects about

Chronic Fatigue Syndrome and Rituximab

IV rituximab has been used to treat chronic fatigue syndrome. A large, well-designed new study shows it doesn’t work. Chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis (ME or ME/CFS), is a poorly-understood condition characterized by profound fatigue and a constellation of other symptoms. The diagnostic criteria, cause, pathophysiology, and treatment have been embroiled

Just How Addictive Are Opioids?

There is an opioid epidemic, with increasing overdose deaths from both prescription drugs and illegal drugs. Just how addictive are opioids? It appears they are safe when used appropriately, but there is a high risk of abuse, and they are deadly when misused, especially OxyContin.  We are in the midst of an opioid epidemic. Prescription

Osteopenia: When Does Decreased Bone Density Become a Disease Requiring Treatment?

Osteoporosis is routinely treated with bisphosphonates to prevent fractures. A new study suggests that osteopenia should be treated too. But questions remain.  Bisphosphonate drugs have been shown to increase bone density and prevent fractures in postmenopausal women with osteoporosis (remember Sally Field in those ads for Boniva?) but what about women with milder decreases in

Health Freedom, Right to Try, and Informed Consent

Starting with the Terrible Twos, when toddlers hear the word “No” on a regular basis, people don’t like to be told they can’t do something. They often believe government regulations interfere with their rights. The government requires vaccinations for school attendance; parents complain that they should be able to make their own decisions about whether

More About Flu Vaccine

More evidence that flu shots work, that they are safe during pregnancy, and that they don’t cause autism. Last week I wrote about influenza vaccines. I provided a link to a site summarizing the evidence that flu shots are effective and safe. Nevertheless, one reader commented “The flu vaccine does not work,” citing a Cochrane

Flu Shots: It’s That Time Again

Flu shots are safe and effective. They not only protect the recipient but others in the community who are more vulnerable. Get your flu shot! It’s that time of the year again: time to get our flu shots. Flu shots are undeniably safe and effective, although they are not as effective as we might wish.

Estrogen Matters

Hormone replacement therapy in menopause is safer and more effective than we have been led to believe. A new book examines the evidence and sets the record straight. Estrogen replacement stops hot flashes cold and is a veritable Fountain of Youth. Estrogen replacement is dangerous: it kills women. It prevents heart disease. It causes heart

Smoking Cessation

Smoking is the leading cause of preventable disease and death. There are effective pharmacological and non-pharmacological methods to help people stop smoking. Conventional medicine is often accused of ignoring prevention, just letting preventable diseases develop, and then only treating symptoms. And the Science-Based Medicine blog is often accused of ignoring the flaws of conventional medicine

Do Sunscreens Cause Cancer?

The diagnostic characteristics of melanoma A reader asked me to look into the claims that sunscreens cause cancer, especially the claims made by Elizabeth Plourde. When our own Scott Gavura evaluated sunscreens, he concluded: The data on sunscreen use and cancer risk are complex, but on balance suggest that the short-term and long-terms benefits of