IOM Recommends Replacing CFS with SEID

Chronic fatigue syndrome (CFS) is a controversial diagnosis that has also been called myalgic encephalomyelitis (ME or ME/CFS), post-viral fatigue syndrome (PVS), chronic fatigue immune dysfunction syndrome (CFIDS), Iceland disease, “yuppie flu,” and many other names. A new report from the Institute of Medicine (IOM) says that none of those names really fit the disease and recommends

Placebo, Are You There?

Note: This was originally published as “Placebo, es-tu là?” in Science et pseudo-sciences 294, p. 38-48. January 2011. It came to my attention in the course of an e-mail correspondence with the editors of that magazine, where one of my own articles was published in French translation in January 2015. I thought this was the best explanation of placebo

Is the Ebola Crisis a Reason to Skip RCTs?

In a recent “Perspective” article in The New England Journal of Medicine, three physicians (Drs. Cox, Borio, and Temple) make a strong case for not letting the rush to save Ebola patients tempt us to deviate from good science and skip the randomized controlled trial (RCT). Their arguments cut to the essence of the scientific approach to medicine,

Smokey the Bear Medicine and Prevention

When I was an intern, we used to joke that we were practicing “Smokey the Bear” medicine: stamping out forest fires. Patients would wait until a spark of disease had developed into a dangerous flame, and then they’d expect us to deal with it. We were mostly doing disaster control, and we wished we could

Oxygen Myths That Refuse to Die

One of my early forays into the world of pseudoscience was an investigation of “Vitamin O” (the O stands for oxygen). The story is hilarious; please click and read; I guarantee you won’t be able to read it without at least a chuckle. Vitamin O is still for sale; it’s even available on Amazon.com. You can

An Egregious Example of Ordering Unnecessary Tests 

Last week I wrote about doctors who order unnecessary tests, and the excuses they give. Then I ran across an example that positively flabbered my gaster. A friend’s 21-year-old son went to a board-certified family physician for a routine physical. This young man is healthy, has no complaints, has no past history of any significant health

Rope Worms: C’est la Merde

Rope worms are rope-like meter-long human intestinal parasites that were only recently discovered in the returns of cleansing enemas and are often reported after coffee enemas. Strangely, no one had ever noticed them until 2009. They have never been observed during endoscopy or surgery, during medical bowel cleansing in preparation for surgical or imaging procedures,

Different Strokes for Different Folks: Assessing Risk in Women

You may have noticed that men and women are different. I hope you have noticed. As the French say, vive la différence! It’s not just that one has dangly bits and the other has bumpy chests. Or that one has to shave a beard and doesn’t like to ask for directions while the other has menstrual periods

Doctors Are Not “Only Out to Make Money”

There’s an old joke about the doctor whose son graduates from medical school and joins his practice. After a while the son tells his father, “You know old Mrs. Jones? You’ve been treating her rash for years and she never got better. I prescribed a new steroid cream and her rash is gone!” The father

How to Talk to People About CAM

Recently a correspondent asked me for advice about his parents. He said they use things like homeopathy, acupuncture, and copper bracelets. They use conventional medicine too, but it seems to be a 50/50 approach that gives each an equal weighting. He has tried to talk to them about things like homeopathy and the placebo effect,