Chronic Fatigue Syndrome and Rituximab

IV rituximab has been used to treat chronic fatigue syndrome. A large, well-designed new study shows it doesn’t work. Chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis (ME or ME/CFS), is a poorly-understood condition characterized by profound fatigue and a constellation of other symptoms. The diagnostic criteria, cause, pathophysiology, and treatment have been embroiled

Chronic Fatigue Syndrome: Rituximab Revisited

Three years ago I wrote about an experimental treatment for chronic fatigue syndrome (CFS): rituximab (brand name Rituxan). I was concerned that doctors who offered it, like Andreas Kogelnik, were jumping the gun by offering it before the evidence was in, and that they might be putting patients at risk. A correspondent who has been following the