The Best Science from The New England Journal of Medicine

The editor-in-chief of The New England Journal of Medicine has selected a dozen articles published during his tenure that epitomize the best of science-based medicine. This is the Science-Based Medicine blog, but all too often we talk about things that are not science-based medicine. Examining what is not science-based medicine is a good way to better understand what science-based

Smart Jane Test of Vaginal Health: Clever Marketing, Questionable Science

Gonorrhea. The SmartJane test is not the way to diagnose this. The uBiome company’s SmartJane test claims to use state-of-the-art DNA sequencing technology, machine learning, artificial intelligence, statistical genetics, algorithms, and other proprietary innovations so women can assess their own vaginal health. Customers collect samples with vaginal swabs and mail them in for processing. They

Pseudoscience in Child and Adolescent Psychotherapy

This new book addresses the neglected field of research on child and adolescent psychotherapy and does an excellent job of distinguishing treatments that have been proven to work from treatments that are based on pseudoscience. Pseudoscience in Child and Adolescent Psychotherapy: a Skeptical Field Guide is a new book with multiple authors, edited by Stephen

Chiropractor Treating Concussions for Earlier Return to Play

A chiropractor is using questionable diagnostic and therapeutic measures to return athletes to play sooner after a concussion. Not a good idea. A science teacher contacted me with concerns about a story he saw on his local TV news. It featured a chiropractor in his area who is treating athletes with concussions. He claims that

Chronic Fatigue Syndrome and Rituximab

IV rituximab has been used to treat chronic fatigue syndrome. A large, well-designed new study shows it doesn’t work. Chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis (ME or ME/CFS), is a poorly-understood condition characterized by profound fatigue and a constellation of other symptoms. The diagnostic criteria, cause, pathophysiology, and treatment have been embroiled

Medical Apartheid

Harriet Washington’s book tells the dark history of medical experimentation on black Americans. It also reveals broader problems of inequality, poor science, and human failures. Harriet Washington In a recent post, Clay Jones reminded us that “the unconscious need to avoid cognitive dissonance serves as a powerful motivation to rationalize even the most horrific beliefs

Great Courses: Skeptic’s Guide to Health, Medicine, and the Media

The Great Courses offers continuing education for adults in a wide variety of subjects. They search out the best college professors and have put together over 500 expertly-produced video courses. You can buy them individually or subscribe to The Great Courses Plus, which gives you unlimited access to all their courses. I am a long-time customer,

An HBO Documentary about the Theranos Fraud Raises Concerns

Elizabeth Holmes founded Theranos to develop a device that could do 200 tests on a single drop of blood in a minute. She lied; it failed; she is being tried for fraud and conspiracy. The HBO documentary The Inventor tells the story but has some flaws. We can learn lessons from what happened. Alex Gibney’s film The Inventor:

For Discussion: Should I Write Only About Fake Stuff If It Is Well-Known?

A person who describes himself as a “pseudoscience fighter” e-mailed me to chastise me for writing about Prodovite last week. He felt compelled to offer me some advice. He made some good points; but they were things I had already thought about, and they didn’t change my mind. I thought it might be useful to open

The “Evidence” for Prodovite Is Junk Science

Prodovite is a liquid nutritional supplement marketed as “nutrition you can feel.” The claims are pseudoscientific nonsense and the single unblinded clinical study is junk science that relies on a bogus test: live cell microscopy. I recently got an email asking: What are your thoughts on this supplement? It seems to be a very good